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For patients without neurological involvement , hydroxocobalamin 1 mg is administered intramuscularly three times a week for 2 weeks, followed by maintenance injections every three months for life (if due to pernicious anaemia or other non-dietary cause)

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Preclinical studies have demonstrated no significant toxicity even at doses far exceeding therapeutic ranges

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[DOI] [PubMed] [Google Scholar] 110.Sengenes C, Bouloumie A, Hauner H, Berlan M, Busse R, Lafontan M, et al

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